Charles B. Holmes, MD, MPH, is former CIDRZ Director and CEO.
He is Associate Professor of Medicine and International Health at Johns Hopkins University.

Dr Holmes previously served for five years in leadership positions in the Office of the U.S. Global AIDS Coordinator of the Department of State, most recently as Deputy US Global AIDS Coordinator and Chief Medical Officer involved in coordinate the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), a multi-agency response to the HIV pandemic.

He is a physician trained in internal medicine, infectious disease, epidemiology and public health policy, and continues to practice medicine as a member of the medical faculty at Johns Hopkins University. He previously served on the faculty at Massachusetts General Hospital and Harvard Medical School, and spent two years leading the development of new HIV treatments in the biotechnology industry. He is well known for his work to define rates of decline of immune function among individuals living with HIV and to quantify their risks of related infections to allow for better targeting of available treatments, examining sex differences in TB risks, studies examining the costs and cost-effectiveness of optimized interventions for the HIV response in low-resource regions, and for his research and writing on health systems innovations. His research findings have been used in the formulation of WHO Guidelines and he has served on numerous guidelines committees of WHO, and the Scientific Advisory Committee of the Center for Global Health Policy of the Infectious Diseases Society of America. He received his Master of Public Health degree from the University of Michigan, and Medical degree from Wayne State School of Medicine.