Charles B. Holmes, MD, MPH, is former CIDRZ Director and CEO. He is Co-Director of the Center for Global Health & Quality at Georgetown University and Associate Professor of Medicine and International Health at Johns Hopkins University.

Prior to serving as CIDRZ CEO for four years, Dr Holmes was in leadership positions in the Office of the U.S. Global AIDS Coordinator of the Department of State, most recently as Deputy US Global AIDS Coordinator and Chief Medical Officer of the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) program.

Dr Holmes is a physician trained in internal medicine, infectious diseases, epidemiology and public health policy, and continues to practice medicine as a member of the medical faculty at Johns Hopkins University. He previously served on the faculty at Massachusetts General Hospital and Harvard Medical School and spent two years leading the development of new HIV treatments in the biotechnology industry. He is well known for his work to define rates of decline of immune function among individuals living with HIV and to quantify their risks of related infections to allow for better targeting of available treatments, examining sex differences in TB risks, studies examining the costs and cost-effectiveness of optimized interventions for the HIV response in low-resource regions, and for his research and writing on health systems innovations.