The Centre for Infectious Disease Research in Zambia (CIDRZ), joined a team of Scientific Researchers in Zambia at the National Health Research Authority (NHRA), fourth quarter meeting for the year 2019.
NHRA is a coordinating body in facilitating Research in Zambia. It hosts quarterly scientific research meetings to provide a platform for researchers to disseminate research results and relevant health information to the entire research Community, program officers and policy makers.
During the fourth and last quarter research meeting for the year 2019, CIDRZ Research Department made a presentation on “the Effect of extended dose intervals on the immune response to oral cholera Vaccine in Zambia”.
The presentation which was made by Mr John Mwaba, a CIDRZ Research Fellow, was based on results from a research carried out between November 2017 and October 2018, on the “Flexibility of Oral Cholera Vaccine Dosing Interval: A non- inferiority trial – Lukanga Swamps, Zambia.”
The objective of the research was to evaluate the differences in individuals who received the second dose of the Oral Cholera Vaccine (Sanchol) at different intervals: 2 weeks vs 6 months following the first dose of vaccine.
Mr Mwaba said the results of the research showed that, a second dose of the Vaccine given 6 months apart were higher compared to those given 2 weeks apart.
He noted, that the results obtained from the research suggested that a delayed 2nd dose of the OVC (Sanchol) maybe a better booster or in the very least, not inferior to one given at the standard 2 weeks.
Mr Mwaba added that, the spacing between 1st and 2nd dose allows for flexibility in administering the 2nd dose and avert logistical challenges associated with strictly adhering to the manufacturers recommended schedule of 2 weeks apart.
“Look out for the detailed results soon to be published in a peer reviewed journal”