CIDRZ is pleased to welcome Dr Caroline Chisenga PhD Immunology who will be joining the CIDRZ Laboratory in a Post-Doctoral Fellowship position.
Dr Chisenga earned her PhD in Immunology under the Nutritional Support for African Adults Starting Anti-Retroviral Therapy (NUSTART Project) funded by the European and Developing Countries Clinical Trials Partnership (EDCTP). Under the supervision of Professor Paul Kelly of Queen Mary University, London she was able to show for the first time that some T-cell subsets reconstitute slowly after 3 months of ART initiation in malnourished AIDS patients. She also demonstrated the prognostic values of CD4 and CD8 T-cell proliferation and senescent markers as well as described reference ranges for CD4 and CD8 T-cell subsets in HIV-uninfected Zambian adults, and demonstrated that certain T-cell subsets respond to selenium in vitro, effects which are not seen in vivo. These results may help design targeted nutritional interventions that could enhance T-cell proliferation and suggest new possibilities for intervention in order to reduce the risk of early mortality.
Dr Chisenga was recently awarded a Post-Doctoral Fellowship in enteric diseases under the Sanitation and Hygiene Applied Research for Equity (SHARE) project and will join CIDRZ under the mentorship Chief Scientific Officer Dr Roma Chilengi.