Studies 2019-07-08T13:47:28+00:00

Project Title:   An open label randomised controlled trial of two versus three doses of Rotarix™ vaccine for boosting and longevity of vaccine immune responses in Zambia.

Acronym: ROVAS-2

Principal Investigator/

EDCTP Senior Fellow

Roma Chilengi

EDCTP PhD Student

Natasha Makabilo Laban

EDCTP MSc student

Adriace Chauwa

This is an investigator led study to explore the potential value of a third dose of rotavirus vaccination for improving vaccine responses and longer-term protection for immunized infants.

The study is registered at Pan African Clinical Trials Registry and is available via the link: https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3096

Enrolment status:        Completed 212

Current status:             Follow up

Funded by The European & Developing Countries Clinical Trials Partnership (EDCTP)

Project Title: Immunological Characteristics of a Population at Risk of Cholera Before and After 1st and 2nd Dose of Oral Cholera Vaccine.

Acronym:         CHOVAXIM

Principal Investigator/

EDCTP Career

Development Fellow

Caroline Chisenga

EDCTP PhD Student

John Mwaba

EDCTP MSc student

Harriet Ng’ombe

This study aims to explore host genetic factors, HIV and nutritional status on uptake of Oral Cholera Vaccine (OCV) of a Population at Risk of Cholera in Lukanga Swamp, Zambia.

Enrolment status:        Completed 222

Current status:             Sample analysis and participant follow up

Funded by The European & Developing Countries Clinical Trials Partnership (EDCTP)